Ultra Duration vs Tag 45: How Do They Compare?

By Emily M.| Last updated on April 16, 2024
ultra duration vs tag 45
⏱️ 6 min read

Permanent makeup is essentially tattooing, and when clients start considering a treatment, one of the points that puts them on the fence is the fear of pain. That’s where numbing products step in, ensuring a painless and comfortable experience for every client.

Numbing topicals come in many forms and formulas, but choosing the right product is important for every PMU artist. So, if this is something that sparked your interest, it’s time to get familiar with two best-selling pain stoppers for PMU: Ultra Duration and Tag 45.

Meet Ultra Duration: A Swipe Away from Comfort

This powerful little bottle is a powerhouse when it comes to reducing pain and discomfort. It guarantees fast and effective results, making it easy for PMU artists to rely on this wonderful product. Ultra Duration Secondary Numbing Liquid is made for use on broken skin.

Here’s a guide through the category of secondary numbing.

With its groundbreaking formula, it surpasses almost every other numbing product and that’s why it’s a cult favorite among microblading artists all over the world. Its potency and efficacy make this product truly special.

Ultra Duration doesn’t just reduce pain and discomfort, it also goes a mile further to minimize swelling and irritation. This additional advantage makes it worth trying to reduce the client’s distress and help with the healing process.

What Treatments Is Ultra Duration Used For?

It’s suitable for use on brows, lips, and areolas. By using Ultra Duration during eyebrow microblading and PMU sessions, you are providing your clients with comprehensive care and boosting their overall experience!


This product has become a staple in almost every PMU artist’s kit due to its amazing benefits. Here are just a few of them:

  • Fast acting: When applied to the broken skin, it acts almost immediately, alleviating pain and discomfort within minutes.
  • High efficacy: With Ultra Duration, there’s no need to worry whether the applied amount will be enough. It’s very powerful and strong, making needles feel like feathers!
  • Longevity: The numbing effect lasts longer, and so does the client’s comfort.
  • Personalized usage: Ultra Duration can be applied 2-3 times during the session to extend the numbing sensation.

How to Use

Due to its amazing active ingredients, you can use Ultra Duration without hassle. It does the work for you! Here’s how it works:

Step 1 – Clean the desired area and apply a small amount on broken skin, ideally with a microbrush. There’s no need to occlude the area with plastic wrap.
Step 2 – Wait 2-3 minutes for it to start working.
Step 3 – Remove any excess product from the treated area.
Step 4 – You can now resume with the treatment.

Be aware that certain skin reactions like irritation and sensitivity may occur.


Ultra Duration is different from other secondary numbing topicals because it’s a liquid, not a gel. So if you’re using it for the first time, know that it’s quite runny and thin in consistency.

Who Shouldn’t Be Exposed to Ultra Duration?

Ultra Duration is not suitable for clients who have a history of liver problems or impairments. It’s also not recommended to use on individuals who have known allergies to any of the active ingredients.

It shouldn’t be used on pregnant and breastfeeding clients due to its powerful effects and potential complications.

It shouldn’t be used in large quantities, especially on blistered or raw areas of skin.

Meet Tag 45: The Path to Painless Precision

This product is a staple in many tattooing artists’ kits and has been for decades. Addressing the need for painless microblading sessions, Tag #45 Topical Anesthetic has a gel-like consistency that can be spread easily to the desired area.

It’s specifically designed for artists to use in tattooing salons and studios, offering the perfect solution for everyone who seeks a pain-free PMU experience. It’s gentle and extremely effective at the same time, combining the best of both worlds.

The best part is that it works almost immediately and significantly decreases the intensity of the microblading or micropigmentation process.

Tag #45 contains epinephrine (adrenaline) – a vasoconstrictor.

This ingredient temporarily shrinks blood vessels and diminishes blood flow into the area. As a result, the skin doesn’t bleed and it turns white – which is how many artists achieve perfect after images free of redness.

What Treatments Is Tag #45 Used For?

Perfect for any area, including brows, lips, eyes, and areolas, this powerful topical anesthetic functions as a secondary numbing agent as it reduces pain and swelling.


There is an array of advantages this tiny bottle comes with, but these are the ones definitely worth mentioning:

  • Visibility: If you’re more of a visual learner, this product will quickly become your favorite. It leaves a visible cast that shows that it’s working.
  • Targeted application: It’s designed to be applied on broken skin and provides relief fast.
  • Personalized usage: Tag #45 can be used several times during a session, depending on the client’s pain tolerance level.
  • Soothing effects: Due to its active ingredients, it effectively minimizes pain, redness, discomfort, and swelling.

How to Use

Using Tag #45 is a pretty straightforward process, so it shouldn’t be too hard to get accustomed to it.

Step 1 – Apply a sparing amount of the gel on broken skin, ideally with a microbrush. Never apply it on closed skin since it’s ineffective in that case.
Step 2 – Wait until the anesthetic starts working. It usually takes about two minutes, but you can wait a bit more if the client is not comfortable enough.
Step 3 – Wipe the gel away before resuming to see the canvas clearly.
Step 4 – Start creating the magic!

It’s normal for skin irritation to occur when using Tag #45 due to skin pulling, stretching, etc, but this happens in combination to the inevitable skin trauma of the blading/needling process.

Avoid contact with eyes, that is very important. If that happens, rinse the eyes with lukewarm water and an eyewash and advise the client to seek help from a doctor.

What Some Artists Do

Microblading requires crisp, firm skin to get the strokes right, and many pre-numbing products soften it. So what many microblading artists do is do a very light first pass without any numbing, and then go straight for Tag 45.

This is okay to do if your client can handle it. Most can, since the pressure can be really light for the first pass – you just need to open the skin a bit.

Who Shouldn’t Be Exposed to Tag #45?

People who have had any liver problems or impairments in the past shouldn’t be numbed with this product, as well as those with known allergies to any of the active ingredients (lidocaine or epinephrine).

You also can’t use it on pregnant and breastfeeding clients.

So, Which One to Choose?

If you’re a PMU artist, you probably have a favorite by now, but if not, it’s time to do a final comparison of these two products.

Ultra Duration Secondary Numbing Liquid is not recommended for eyelids but can be used for eyebrow microblading and PMU, lip blush, and areola tattoos. It’s more popular among microblading artists.

The three active ingredients are lidocaine, epinephrine, and tetracaine, which makes this product very effective and potent.

Tag #45 can be used on broken skin for all eyebrow techniques, lip blush, permanent eyeliner, and areola tattoos. It has a gel-like consistency, a bit thicker than Ultra Duration.
With its two active ingredients, lidocaine, and epinephrine, it works as a secondary numbing agent.

The one you need to choose depends entirely on your needs and skill set. We are sure that whichever ends up in your hands, you’re going to love it!

ultra duration vs tag 45 pros and cons

What You Should Know About the Whole PainStoppers Range

PainStoppers AKA UnitDose topicals were created by Dr. Linda Dixon, MD, an anesthesiology specialist who dedicated a significant part of her career to developing and improving permanent makeup techniques and products used for them.

Dr. Linda Dixon, MDDr. Linda Dixon, MD

So, the whole range is 100% reliable and trustworthy.

Her formulas have truly revolutionized the PMU industry, finding their staple place on countless trays in countless salons. And as a logical next step – they’re often copied and there’s a lot of counterfeit products out there.

On PMUHub, you can buy all the artists’ favorites without any doubt about their origin – we get the supply directly from the manufacturer and make sure they arrive to you fresh, quickly, and in perfect condition!



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